Rapid and Low-Cost Microfluidic Devices Fabricated Using a 3D Printer

论文详情

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官方摘要 (Official Abstract)

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“Microfluidic has emerged as a strong tool in several domains, including biology, chemistry, and medicine. However, manufacturing microfluidic devices using traditional techniques such as photolithography and soft lithography may be costly and time-consuming. In this research, we described a low-cost microfluidic device production approach based on a 3D printer. The 3D printer employs digital light precision technology to produce microfluidic devices with extreme precision and accuracy. Using this technology, microfluidic devices are created, showcasing its potential for usage in lab-on-a-chip and sensor applications. Our findings show that the 3D printer can produce high-quality microfluidic devices for a substantially cheaper cost than previous approaches.”

中文摘要翻译：

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微流控技术（Microfluidics）在生物学、化学及医学等诸多领域已成为极为重要的科研与诊断工具。然而，采用传统的光刻技术和软光刻（如聚二甲基硅氧烷 PDMS 倒模）等微纳加工方法制造微流控芯片往往成本高昂且生产周期极长。在本研究中，我们提出了一种基于高精度 3D 打印技术的低成本微流控芯片高效制造方案。该 3D 打印系统采用数字光精密成型技术（Digital Light Processing / DLP），能够以极高的精度和准确度一体化直接打印出内部微通道复杂的微流控芯片。实验验证表明，利用该工艺成型的微流控器件具备优异的密封性与微通道精度，展现出在芯片实验室（Lab-on-a-Chip）和在线传感器集成检测中的巨大应用潜力。研究结果证明，桌面级 3D 打印技术能够以极高的效率生产出高质量微流控芯片，其成本相比常规微纳加工工艺实现了大幅降低。

关键词 (Keywords): Microwave antennas, Color, Three-dimensional printing, Radar antennas, Telecommunications, Printers, Resins, pH measurement, Microfluidics, Testing, 3D printer, microfluidic device, low cost, rapid.

技术亮点与核心创新

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• 数字光处理 (DLP) 超高精度加工： 采用高分辨率 DLP 光固化 3D 打印技术，一体成型复杂的三维微流道网络，彻底避免层间剥离与微流体渗漏。
• 替代昂贵洁净室工艺： 免除对半导体洁净室、光刻掩膜版以及硅片/PDMS软光刻流程的依赖，极大地降低了微流控芯片的研发准入门槛。
• 超快迭代原型开发 (Rapid Prototyping)： 实现了从 CAD 三维结构设计到功能芯片测试完成仅需数小时的敏捷化研发流程。
• 多应用场景验证： 成功拓展应用至芯片实验室化学混合分析及实时 pH 传感器集成系统。

推荐引用 (Citation)

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@inproceedings{Hertanto2024Microfluidic,
  author    = {Hertanto, T. L. O. and Kurniawan, E. D. and Oktaviana, A. T. and Jessiena, C. C. and Toba, J. P. and Muhammad, Riki},
  title     = {Rapid and Low-Cost Microfluidic Devices Fabricated Using a 3D Printer},
  booktitle = {2024 International Conference on Radar, Antenna, Microwave, Electronics, and Telecommunications (ICRAMET)},
  year      = {2024},
  pages     = {216--221},
  address   = {Bandung, Indonesia},
  publisher = {IEEE},
  doi       = {10.1109/ICRAMET62801.2024.10809304},
  url       = {https://doi.org/10.1109/ICRAMET62801.2024.10809304}
}